| TARGETS | |
|---|---|
| GPCRs a | Enzymes d |
| Adrenoceptors | ACE |
| AT1 receptor | Akt |
| Chemerin receptor (ChemR23) | AMPK |
| ETA receptor | COX |
| Voltage‐gated ion channels b | eNOS |
| BKCa (KCa1.1) channel | ERK |
| Kv7 channels | mTOR |
| Nuclear hormone receptors c | PKC |
| PPARγ | Rho kinase |
| LIGANDS | |
|---|---|
| Adiponectin | IL‐10 |
| Ang 1‐7 | Insulin |
| Ang II | Leptin |
| Adrenaline | MCP‐1 |
| Chemerin | NO |
| cGMP | Noradrenaline |
| ET‐1 | PGE2 |
| Hydrogen peroxide | RANTES |
| Hydrogen sulphide | TNFα |
| IL‐6 | TXA2 |
| IL‐8 |
These Tables list key protein targets and ligands in this article that are hyperlinked to corresponding entries in http://www.guidetopharmacology.org, the common portal for data from the IUPHAR/BPS Guide to PHARMACOLOGY (Southan et al., 2016), and are permanently archived in the Concise Guide to PHARMACOLOGY 2015/16 (a,b,c,dAlexander et al., 2015a,b,c,d).