Figure 1.
Geometry and Characteristics of Murine Mammary Glands Revealed by Quantitative Reconstructions
(A) Quantitative reconstruction (top) and outline (bottom) of a fourth mammary gland based on Keratin14 (K14) staining (white), reproduced from (Scheele et al., 2017) along with measurements of the fat pad dimensions Lx and Lz (red).
(B) Density profile of ducts along the rescaled antero-posterior axis.
(C) Counting of ductal crossovers (normalized by total number of ductal branches) reveal a low crossing probability.
(D) Experimentally measured ratio between the dimensions of the mammary fat pad (long axis Lx and short axis Lz) and the average length of a branch ld, used for the simulations of the mammary gland. Error bars represent mean and SEM. Scale bar, 5 mm.
See also Figure S1.