Table 1.
Estimated carcinogenesis parameters for 20 most prevalent cancer types.
| Cancer type | k | b | A/1000 | R2 |
|---|---|---|---|---|
| Number of carcinogenic events ± s.e.m. | Average time between events, years ± s.e.m. | Maximal populational susceptibility, % ± s.e.m. | Goodness of fit | |
| Prostate | 41 ± 1 | 1.83 ± 0.00 | 26.40 ± 0.18 | 0.9992 |
| Lung and bronchus | 30 ± 2 | 2.75 ± 0.01 | 16.44 ± 0.24 | 0.9981 |
| Colon and rectum | 10 ± 1 | 13.75 ± 0.17 | 66.93 ± 3.80 | 0.9991 |
| Breast | 9 ± 1 | 10.71 ± 0.09 | 20.44 ± 0.46 | 0.9981 |
| Bladder | 21 ± 1 | 4.59 ± 0.02 | 9.93 ± 0.17 | 0.9995 |
| Non-Hodgkin lymphomas | 8 ± 1 | 19.26 ± 0.58 | 31.21 ± 3.90 | 0.9964 |
| Uterus | 20 ± 1 | 3.67 ± 0.02 | 3.77 ± 0.05 | 0.9954 |
| Pancreas | 15 ± 1 | 7.07 ± 0.01 | 7.15 ± 0.06 | 0.9999 |
| Melanoma | 4 ± 1 | 81.01 ± 7.38 | 100 | 0.9954 |
| Leukaemias | 8 ± 2 | 23.56 ± 1.09 | 49.57 ± 10.93 | 0.9957 |
| Kidney | 15 ± 1 | 5.75 ± 0.04 | 3.69 ± 0.07 | 0.9971 |
| Ovary | 8 ± 1 | 13.66 ± 0.12 | 5.40 ± 0.13 | 0.9989 |
| Stomach | 11 ± 1 | 11.51 ± 0.15 | 7.25 ± 0.42 | 0.9986 |
| Oral cavity | 13 ± 1 | 6.32 ± 0.03 | 2.29 ± 0.03 | 0.9983 |
| Myeloma | 16 ± 1 | 6.14 ± 0.03 | 2.67 ± 0.06 | 0.9992 |
| Oesophagus | 20 ± 0 | 4.25 ± 0.00 | 1.27 ± 0.00 | 0.9999 |
| Liver | 13 ± 2 | 6.67 ± 0.11 | 1.45 ± 0.07 | 0.9863 |
| Brain | 4 ± 1 | 76.69 ± 13.77 | 26.34 ± 14.52 | 0.9777 |
| Thyroid | 5 ± 0 | 14.67 ± 0.24 | 1.52 ± 0.04 | 0.9734 |
| Larynx | 24 ± 1 | 3.15 ± 0.01 | 0.71 ± 0.01 | 0.9989 |
The parameters are determined for the Erlang distribution fitted to actual cancer incidence data (see Fig. 2). Cancer types are listed in the order of decreasing incidence.