Fig. 2.

Encapsulation of GOX and HRP in a multi-compartmental particle. a Bright-field microscopic image of GOX@HRP. b Confocal scanning laser microscopic images of GOX@HRP in x–y, x–z and y–z planes, along with a 3D model of GOX@HRP. The GOX and HRP were labeled with rhodamine B isothiocyanate (RBITC, red) and fluorescein isothiocyanate (FITC, green), respectively. Detailed labeling procedures are discussed in Supplementary Methods (Labeling of enzymes with fluorescent dyes). c GOX and HRP release profiles from GOX@HRP in PBS (10 mM, pH 7.0). Scaling bars are 200 μm