Table 5.

Characterization of modules and network in humans with WGCNA using density, centralization and heterogeneity

Module	Density	Centralization	Heterogeneity	Nr nodes	Color coded
${\mathcal{N}}_O$ a
FA/LDLb	0.32	0.19	0.45	17	Blue
HDLc	0.31	0.23	0.55	9	Brown
VLDL/AAd	0.15	0.19	0.72	22	Turquoise
Complete	0.07	0.11	0.76	58
${\mathcal{N}}_B$ b
VLDLe	0.77	0.11	0.11	8	Yellow
HDLg	0.67	0.15	0.15	5	Black
LDL/IDLh	0.63	0.18	0.35	11	Blue
FA/lipidsi	0.59	0.16	0.19	13	Turquoise
FA/othersj	0.54	0.15	0.27	9	Brown
FAk	0.20	0.20	0.42	6	Green
AA/lipoproteinsl	0.19	0.16	0.38	6	Red
Complete	0.23	0.17	0.50	58

^aNetwork using the original metabolite values

^bFA/LDL: APOB, DHA, FAW3, FAW3FA, FAW6,IDLC, IDLL, LA, LDLC, LLDLL, MLDLL, PC, SERUMC, SLDLL, SM, TOTPG, XSVLDLL

^cHDL: ALB, APOA1, HDL2C, HDLC, LHDLL, MHDLL, SHDLL, XLHDLL

^dVLDL/AA: ALA, FAW6FA, GLC, GP, HDL3C, ILE, LAC, LDLD, LEU, LVLDLL, MUFA, MVLDLL, PHE, PYR, SERUMTG, SVLDLL, TOTFA, TYR, VAL, VLDLD, XLVLDLL, XXLVLDLL

^eNetwork using BMI-related information

^fVLDL: ALA, LVLDLL, MVLDLL, SERUMTG, SVLDLL, VLDLD, XLVLDLL, XXLVLDLL

^gHDL: ACACE, APOA1, BOHBUT, HDL2C, HDLC

^hIDL/LDL: ACE, IDLC, IDLL, LDLC, LEU, LLDLL, MLDLL, SERUMC, SLDLL, SM, XSVLDLL

ⁱFA/lipids: APOB, FAW3FA, FAW6, GLOL, LA, LAC, LDLD, MUFA, PC, PYR, SHDLL, TOTFA, TOTPG

^jFA/others: GLC, GP, HDLD, ILE, LHDLL, PHE, TYR, VAL, XLHDLL

^kFA: CIT, DHA, FAW3, FAW6FA, GLN, MHDLL

^lAA/lipoproteins: ALB, CREA, GLY, HDL3C, HIS, UREA