Table 1.
Study | Study design | Population | Duration | Resveratrol group | Control group | Outcomes |
---|---|---|---|---|---|---|
Brasnyo et al. | Randomized placebo-controlled double-blinded parallel clinical trial | N = 19 patients with T2DM | 4 weeks | N = 10;10 mg/d | N = 9; Placebo | Fasting plasma glucose, fasting insulin, HbA1c, HOMA-IR |
Bhatt et al. | Open-label, randomized, controlled trial |
N = 57 patients with T2DM |
3 months | N = 28;250 mg/d | N = 29; Empty-control | Fasting plasma glucose, HbA1c |
Movahed et al. | Randomized placebo-controlled double-blinded parallel clinical trial |
N = 64 patients with T2DM |
45 days | N = 33;1 g/d | N = 31; Placebo | Fasting plasma glucose, fasting insulin, HbA1c, HOMA-IR |
Goh et al. | Randomized double-blind |
N = 10 patients with T2DM |
12 weeks | N = 5;3 g/d | N = 5; Placebo | Fasting plasma glucose, fasting insulin, HbA1c, HOMA-IR |
Tome-Carneiro et al. | Randomized placebo-controlled triple -blinded parallel clinical trial | N = 35 patients with T2DM | 12 months |
N = 13; RSV-enriched grape extract (8 mg/d) |
N = 22; Placebo | Fasting plasma glucose, HbA1c |
Bashmakov et al. | Randomized placebo-controlled examiner -blinded parallel clinical trial | N = 24 patients with diabetic foot syndrome | 60 days | N = 14; 50 mg/day | N = 10; Placebo | Fasting plasma glucose, fasting insulin |
Thazhath et al. | Randomized, double-blind, crossover design | N = 14 patients with T2DM | 5 weeks | N = 14;1 g/d | N = 14; Placebo | Fasting plasma glucose, HbA1c |
Timmers et al. | Randomized double-blind crossover study | N = 17 patients with T2DM | 30 days | N = 17;150 mg/d | N = 17; Placebo | Fasting plasma glucose, fasting insulin, HbA1c, HOMA-IR |
Javid et al. | Randomized placebo-controlled double-blinded parallel clinical trial | N = 43 patients with T2DM | 4 weeks | N = 21;480 mg/d | N = 22; Placebo | Fasting plasma glucose, fasting insulin, HOMA-IR |
T2DM type 2 diabetes mellitus, HOMA-IR homeostasis model assessment of insulin resistance, HbA1C glycated hemoglobin A