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. 2017 Sep 1;30(7):479–489. doi: 10.1089/vim.2017.0008

Table 1.

Systematic T Cell Epitope Mapping Studies of E Proteins

Virus Reference Subjects N Peptides Detection Epitope densitya
DFV2 (45) Humans 5 100 Elispot, IFNγ 1.2
JEV (55) Humans 26 62 Elispot, IFNγ 3.3
YFV (56) C57BL/6 mice N/A 50 Flow, IFNγ 1
YFV (30) BALB/c mice 3–5 81 Elispot, IFNγ <6
YFV (18) Humans 40 83 Tetramer flow 3.6b
TBEV (49) Humans 34 124 Elispot, IL-2 5c
WNV (4) C57BL/6 mice 2–5 100 Flow, IFNγ <2
WNV (17) Humans 40 83 Tetramer flow 3.6d
a

Average number of epitopes in E detected per subject or tetramer allele.

b

Seven alleles tested.

c

Median reported for a subset of subjects.

d

Ten alleles tested.

DFV2, dengue fever virus type 2; JEV, Japanese encephalitis virus; YFV, yellow fever virus; WNV, West Nile virus; TBEV, tick-borne encephalitis virus; IFN, interferon; IL, interleukin; N/A, not available.