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. Author manuscript; available in PMC: 2017 Sep 23.
Published in final edited form as: Chem Rev. 2015 Nov 9;115(22):12546–12629. doi: 10.1021/acs.chemrev.5b00434

Table 45.

Some examples of FAM labeled caspases FMK inhibitors

FLICA sequence Structure Target Ref.
FAM-DEVD-CH2F
517 		graphic file with name nihms905431t219.jpg Casp-3, -7, -8 17,436
FAM-VEID-CH2F
518 		graphic file with name nihms905431t220.jpg Casp-6 17,429
FAM-VDVAD-CH2F
519 		graphic file with name nihms905431t221.jpg Casp-2 17
FAM-LETD-CH2F
520 		graphic file with name nihms905431t222.jpg Casp-8 17
FAM-YVAD-CH2F
521 		graphic file with name nihms905431t223.jpg Casp-1, 3, 6, 7 17,389
FAM-VAD-CH2F
516 		graphic file with name nihms905431t224.jpg Casp-3, 6, 7 83,429