Table 3.
Details of 9 patients with low albumin and high CRP
| No. | Age | Primary disease | Stem cell source | Conditioning | Duration from transplantation to infection (days) | Engraftment | CRP (mg/dl) | Albumin (g/dl) | Severe sepsis or septic shock | Initial source of infection | Subsequent progression to pneumonia (days) | Treatment | Survival (days) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 32 | AML | uBM | BU+CY+TLI | 124 | Yes | 11.6 | 1.9 | - | Sources unknown | Yes (1) | MINO | 12 |
| 2 | 58 | AML | CB | Flu+Mel+TBI | 26 | No | 14.4 | 2.3 | Severe | Pneumonia | - | 2 | |
| 3 | 54 | AML | CB | CA+CY+TBI | 15 | Yes | 18.5 | 2.5 | Severe | Sources unknown | Yes (5) | MINO | 7 |
| 4 | 70 | CMLBC | CB | Flu+Mel+TBI | 20 | No | 40.8 | 2.9 | Severe | Pneumonia | CPFX | 2 | |
| 5 | 69 | AML | uBM | Flu+Mel+TBI | 11 | Yes | 19.8 | 2.6 | Shock | Pneumonia | - | 2 | |
| 6 | 64 | PMF | uBM | Flu+Mel+TBI | 34 | No | 25.3 | 1.6 | Severe | Pneumonia | CPFX | 2 | |
| 7 | 57 | FL | uPB | Flu+CY+TBI | 10 | No | 15.9 | 2.4 | Shock | Sources unknown | Yes (8) | CPFX+MINO | 10 |
| 8 | 30 | AML | uBM | CY+TBI | 373 | Yes | 23 | 1.6 | Shock | CLABSI | Yes (1) | CPFX+MINO→ST+MINO | 2 |
| 9 | 56 | AML | uBM | Flu+BU+TBI | 17 | No | 17.8 | 1.6 | Severe | Pneumonia and cellulitis | TGC→ST+TGC | 32 |
Abbreviations: AML acute myeloid leukemia, CMLBC chronic myeloid leukemia blast crisis, PMF primary myelofibrosis, FL follicular lymphoma, uBM unrelated-bone marrow, CB cord blood, uPB unrelated-peripheral blood, BU busulfan, CY cyclophosphamide, TLI total lymphoid irradiation, Flu fludarabine, Mel melphalan, TBI total body irradiation, CRP c-reactive protein, CLABSI central-line associated blood stream infection, MINO minocycline, CPFX ciprofloxacin, ST trimethoprim-sulfamethoxazole, TGC tigecycline