Table 1.
Clinical characteristics of the 211 colon cancer patients according to High or Low miR-19b-3p
| Variable | Total (n = 211) | miR-19b-3p expression | P value | |
|---|---|---|---|---|
| Low (n = 115) | High (n = 96) | |||
| Age | ||||
| < 65 y | 89 | 47 | 42 | 0.721 |
| ≥ 65 y | 122 | 68 | 54 | |
| Gender | ||||
| Male | 72 | 45 | 27 | 0.637 |
| Female | 139 | 70 | 69 | |
| Location | ||||
| Left | 148 | 77 | 71 | 0.521 |
| Others | 63 | 38 | 25 | |
| T stage | ||||
| T1 + T2 | 17 | 9 | 8 | 0.764 |
| T3 + T4 | 194 | 106 | 88 | |
| N stage | ||||
| N0 | 115 | 80 | 35 | <0.001* |
| N1 + N2 | 96 | 35 | 61 | |
| AJCC stage | ||||
| I + II | 114 | 86 | 28 | <0.001* |
| III + IV | 97 | 29 | 68 | |
| Histologic grade | ||||
| Well Differentiated | 104 | 66 | 38 | 0.032* |
| Poorly differentiated | 107 | 49 | 58 | |
| Venous & Lymphatic invasion | ||||
| No | 197 | 110 | 87 | 0.247 |
| Yes | 14 | 5 | 9 | |
| Peritoneal Dissemination | ||||
| Absent | 184 | 97 | 87 | 0.359 |
| Present | 27 | 12 | 15 | |
| Liver Metastsis | ||||
| Negative | 164 | 96 | 68 | |
| Positive Multinodular | 47 | 8 | 39 | <0.001* |
P value are based on chi-square test
AJCC: American Joint Committee on Cancer
*P < 0.05 was considered significant