TABLE 1.
Demographic data for volunteers in all treatment groupsa
| Characteristic | Values |
||||
|---|---|---|---|---|---|
| Part A (single dose) |
Part B (multiple doses) |
||||
| Group 1 (n = 9) | Group 2 (n = 9) | Groups 3 and 4 (n = 16) | Group 5 (n = 8) | Group 6 (n = 8) | |
| Dose(s) (mg) | 200, 400, 600 | 800, 1,000 | 600 | 800 | 1,000 |
| Mean (SD) age (yr) | 38 (8.2) | 41 (7.5) | 37 (12.0) | 33 (12.8) | 53 (5.9) |
| Mean (SD) body wt (kg) | 79.7 (2.73) | 70.9 (14.5) | 79.4 (13.0) | 77.7 (9.11) | 72.4 (12.1) |
| Mean (SD) ht (cm) | 176 (2.8) | 167 (11.2) | 176 (9.5) | 179 (6.0) | 168 (13.8) |
| Mean (SD) BMI (kg/m2) | 25.7 (1.33) | 25.2 (2.50) | 25.7 (3.08) | 24.2 (2.15) | 25.7 (2.59) |
| Gender (no. of males/no. of females) | 9/0 | 5/4 | 15/1 | 8/0 | 5/3 |
a
Demographic data from n subjects are shown stratified by treatment group. Data for volunteers in groups 3 and 4 are summarized together since both groups received the same dose of finafloxacin.