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. 2017 Sep 22;61(10):e00551-17. doi: 10.1128/AAC.00551-17

TABLE 2.

Genes differentially regulated in the H37RaΔsigB strain versus the wild-type H37Ra strain

Category and gene Descriptiona Fold change Tendency
Growth
    yrb1B Membrane protein 1.54 Up
    yrbE4B ABC transporter permease 1.50 Up
    pabB Aminodeoxychorismate synthase component I 0.54 Down
    MRA_0320 Hypothetical protein 0.54 Down
    MRA_0637 Hypothetical protein 0.57 Down
    MRA_0881 Hypothetical protein 0.58 Down
    mprB Two-component sensor histidine kinase 0.65 Down
    cysD Sulfate adenylyltransferase subunit 2 0.60 Down
    cysN Adenylyl-sulfate kinase 0.65 Down
    MRA_1350 Membrane protein 0.67 Down
    MRA_2389 Hypothetical protein 0.61 Down
    MRA_2684 Antitoxin 0.21 Down
    MRA_2056 Sugar ABC transporter substrate-binding lipoprotein 0.63 Down
    MRA_0067 RNase VapC1 0.59 Down
    MRA_3842 Membrane protein 0.60 Down
    sigB RNA polymerase sigma factor SigB 0.00 Down
Metabolic process
    MRA_1007 Acetyltransferase 1.64 Up
    msrA Peptide-methionine (S)-S-oxide reductase 0.56 Down
    fabD2 Malonyl CoA-ACP transacylase 0.49 Down
    pncA Bifunctional pyrazinamidase nicotinamidase 0.59 Down
Transcriptional regulator
    MRA_0471 Transcriptional regulator 0.53 Down
    MRA_1735 Transcriptional regulator 0.46 Down
    MRA_1828 Transcriptional regulator 1.76 Up
    MRA_2649 Transcriptional regulator 0.54 Down
    MRA_2671 Transcriptional regulator 0.62 Down
    MRA_2909 Transcriptional regulator 1.67 Up
    whiB6 Transcriptional regulator 0.43 Down
a

CoA, coenzyme A.