Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
TP-271 exposure in infected cynomolgus macaques given a single i.v. infusion of 1 mg/kg TP-271 on day 1 or after multiple, once-daily i.v. infusions for 14 or 21 days
| Group | Day | Cmaxa (μg/ml) | AUC0–24a (μg · h/ml) |
|---|---|---|---|
| 1 | 1 | 0.358 (0.064) | 1.87 (0.494) |
| 14 | 0.813 (0.811) | 3.89 (2.42) | |
| 2 | 1 | 0.265 (0.059) | 1.37 (0.218) |
| 21 | 0.426 (0.091) | 2.50 (0.510) |
The data represent means (standard deviations).
