TABLE 4.
Correlation between MICs and Rv0678 mutations among CLO-resistant isolates
| Mutation in Rv0678 | No. of isolates | MIC (mg/liter) |
|
|---|---|---|---|
| BDQ | CLO | ||
| Ser53Pro | 2 | 0.5 | 2–4 |
| Ser53Leu | 1 | 0.25 | 2 |
| Tyr157Asp | 1 | 0.125 | 2 |
| No mutation | 1 | 0.5 | 2 |
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