TABLE 1.

Pooled MIC distributions of four Sporothrix species from 2 to 9 laboratories determined by the CLSI M38-A2 broth microdilution method

Agent	Species	No. of laboratories	Total no. of isolates	No. of isolates with MIC (μg/ml) ofa:
				≤0.03	0.06	0.12	0.25	0.5	1	2	4	8	16	≥32
Amphotericin B	S. schenckiib	9	263	2		5	9	29	100	78	33	3	1	3
	S. brasiliensis	9	486	6		10	64	112	175	100	15	4
	S. globosa	4	75			3	5	8	19	29	6	3		2
	S. mexicana	ID
Itraconazole	S. schenckii	8	194		4	5	22	71	56	17	9	3	2	5
	S. brasiliensis	8	306	2	2	12	19	60	146	38	6		5	16
	S. globosa	4	53			5	10	17	10	9	1		1	3
	S. mexicana	3	13				3	4	2	1
Ketoconazole	S. schenckii	2	92		1	11	12	32	17	16	3
	S. brasiliensis	5	338	6	13	45	64	126	71	13
	S. globosa	ID
	S. mexicana	ID
Posaconazole	S. schenckii	8	301		1	10	15	67	114	55	13	14	8	4
	S. brasiliensis	5	200	2	1	6	13	32	128	14	1			3
	S. globosa	3	59				12	25	12	5	1		2	2
	S. mexicana	ID
Voriconazole	S. schenckii	6	252					3	1	6	17	42	108	75
	S. brasiliensis	7	200					1	9	17	32	79	56	6
	S. globosa	3	41						2	5	10	14	9	1
	S. mexicana	3	11						2	1	2	4	2
Terbinafine	S. schenckii	2	118	2	18	23	26	43	6
	S. brasiliensis	3	368	131	151	75	7	2	2
	S. globosa	3	35	5	16	6	3	4	1
	S. mexicana	ID

^aThe highest number in each row (showing the most frequently obtained MIC or mode) is indicated in boldface.

^bS. schenckii refers to S. schenckii sensu stricto. ID, insufficient data with comparable mode.