Table 1.

Characteristics of trials included in the analysis

Characteristic	Number (%)
Total trials	74
Phase of study
1	4 (5)
2	40 (54)
3	25 (34)
Other	5 (7)
Primary endpoint
Overall survival	27 (36)
Progression-free survival	10 (14)
Other	37 (50)
Primary treatment modality
Surgery	8 (11)
Radiation	9 (12)
Medical therapy	54 (73)
Other	3 (4)
Year of study activation
1986–1995	27 (36)
1996–2005	31 (42)
2006–2016	16 (22)
Archival tumor tissue required	5 (7)
Number of therapies administered
0–1	26 (35)
2–3	32 (43)
4–7	16 (22)