Table 2.
Association between trial characteristics and number of eligibility criteria*
| Characteristic | Median (IQR) | P value |
|---|---|---|
|
| ||
| Primary endpoint | 0.001 | |
| Overall survival | 20 (13–24) | |
| Progression-free survival | 28 (22–31) | |
| Other | 17 (12–23) | |
|
| ||
| Primary treatment modality | 0.02 | |
| Surgery | 9 (7–18) | |
| Radiation | 18 (18–21) | |
| Medical | 20 (17–25) | |
|
| ||
| Year of study activation | <0.001 | |
| 1986–1995 | 16 (10–20) | |
| 1996–2005 | 19 (13–23) | |
| 2006–2016 | 27 (24–31) | |
|
| ||
| Number of therapies administered | 0.05 | |
| 0–1 | 18 (9–22) | |
| 2–3 | 21 (15–24) | |
| 4–7 | 22 (17–28) | |
*
Eligibility criteria quantified by grouping