Table 2.
Summary Table of Mean Thickness and Vessel Density Slope Values in Healthy, Glaucoma Suspect and Glaucoma Eyes
| The rate of change (per year) | Healthy | Glaucoma Suspect | Glaucoma | Difference between Healthy and Glaucoma | Difference between Glaucoma suspect and Glaucoma | |||||
|---|---|---|---|---|---|---|---|---|---|---|
|
| ||||||||||
| Mean (95%CI) | P Value* | Mean (95%CI)) | P Value* | Mean (95%CI) | P Value* | Mean (95%CI) | P Value† | Mean (95%CI) | P Value† | |
| OCT (Thickness, μm/year) | ||||||||||
| Ganglion Cell Complex | −0.92 (−2.15, 0.32) | 0.148 | −0.10 (1.57, 1.38) | 0.899 | −0.44 (−1.57, 1.38) | 0.532 | −0.48 (−2.32, 1.35) | 0.609 | −0.34 (−2.34, 1.66) | 0.740 |
| OCT-A (Vessel Density, %/year) | ||||||||||
| Whole-en-face | 0.29 (−0.82, 1.40) | 0.610 | 0.87 (−0.47, 2.22) | 0.204 | −2.23(−3.52, −0.93) | <0.001 | −2.52 (−0.80, −2.86) | 0.004 | −3.10 (−4.96, −1.24) | 0.001 |
| Superior-en-face | −0.00 (−1.11, 1.11) | 0.998 | 1.04 (−0.30, 2.38) | 0.129 | −1.97 (−3.28, −0.67) | 0.003 | −1.97 (−0.25, −3.68) | 0.025 | −3.01 (−4.88, −1.15) | 0.002 |
| Inferior-en-face | 0.50 (−0.76, 1.75) | 0.441 | 0.74 (−0.77, 2.26) | 0.341 | −2.90 (−4.37, −1.44) | <0.001 | −3.40 (−5.32, −1.48) | <0.001 | −3.65 (−5.73, −1.56) | <0.001 |
| Para Fovea | 0.53 (−0.83, 1.89) | 0.444 | 0.89 (−0.75, 2.52) | 0.292 | −3.13 (−4.70, −1.56) | <0.001 | −3.66 (−5.73, −1.58) | <0.001 | −4.01 (−6.27, −1.75) | <0.001 |
| Para-Temporal | 0.48 (−0.82, 1.79) | 0.471 | 0.75 (−0.77, 2.38) | 0.319 | −1.81 (−0.29, −3.32) | 0.021 | −2.29 (−4.29, −0.29) | 0.026 | −2.61 (−4.79, −0.43) | 0.020 |
| Para-Superior | 0.36 (−1.00, 1.73) | 0.603 | 0.48 (−0.91, 2.40) | 0.378 | −2.00 (−3.58, −0.43) | 0.015 | −2.37 (−4.45, −0.29) | 0.028 | −2.75 (−5.01, −0.49) | 0.019 |
| Para-Nasal | 0.30 (−1.14, 1.74) | 0.686 | 0.74 (−1.00, 2.48) | 0.407 | −3.34(−5.01, −1.67) | <0.001 | −3.64 (−5.84, −1.43) | 0.002 | −4.08 (−6.48, −1.68) | 0.001 |
| Para-Inferior | 0.77 (−0.69, 2.23) | 0.303 | 0.59 (−1.18, 2.35) | 0.517 | −2.73 (−4.42, −1.04) | 0.002 | −3.51 (−5.74, −1.27) | 0.003 | −3.32 (−5.75, −0.88) | 0.009 |
*
p-value representing whether the mean rate of change is significantly different from zero
†
p-value based on post-hoc ANOVA testing using the Tukey’s honest significant difference test
Values with statistical significance are shown in bold.
Abbreviations: CI, confidence interval; OCT, optical coherence tomography; GCC, ganglion cell complex; OCT-A, optical coherence tomography angiography