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. 2017 Aug 12;12(5):643–654. doi: 10.1007/s11523-017-0524-3

Fig. 7.

Fig. 7

Proposed framework illustrating the impact of ixazomib dose on the relative dose intensity (RDI) of lenalidomide (top, blue curve) and on the efficacy of the ixazomib plus lenalidomide and dexamethasone (IRd) regimen (bottom, orange curve). Note, this visual representation is not intended to reflect a quantitative estimation of the dose–response relationship