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Tumor vaccines induce IFN gamma production by CD4 T cells. CD4 T cells were cocultivated with the indicated tumor-derived cells harboring immunomodulators. Concentrations of interferon gamma were determined by Elisa after 96 h of incubation. (−) Only CD4 T cells. Mean of three measurements; error bars indicate SEM, ANOVA, and Dunnett’s multiple comparisons against F10 (*P < 0.05). Experiment performed in triplicate.
