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. 2017 Jun 13;3(8):e000115. doi: 10.1099/mgen.0.000115

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© 2017 The Authors

This is an open access article under the terms of the Creative Commons Attribution 4.0 International License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.

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Fig. 1. — A dataset of 42 genomes is not sufficient to define the L. salivarius pan-genome. The four panels show, with the sequential addition of 42 L. salivarius genomes (x-axis), the decrease in core genes (a; top-left), the increase in total genes (b; top-right), the decrease in new genes (c; bottom-left) and the log of the decrease in new genes (d; bottom-right). Genes are counted as orthologous gene families (percentage identity >=40 and percentage alignment length >=50) except for genes unique to each genome. The order of addition of genomes has been permuted 1000 times. Red dots show the variation in values while black dots show the median value. An alpha value of 0.44 shows that the pan genome of L. salivarius is open (α<1).