Table 3.
parameter |
groups
|
* P-value | |||
---|---|---|---|---|---|
HCG | Con | Pio | RDE | ||
myristic acid (μmol/L) | 1.07±0.01 | 1.12±0.06 | 1.2±0.06 | 1.33±0.1 | 0.983 |
palmitic acid (μmol/L) | 5.9±0.57 | 11.1±2.6 | 5.1±0.18 | 9.39±0.82 | 0.034 |
palmitoleic acid (μmol/L) | 1.06±0.04 | 1.4±0.12 | 1.1±0.01 | 1.59±0.49 | 0.936 |
stearic acid (μmol/L) | 1.3±0.12 | 2.7±0.12 | 2.06±0.11 | 2.2±0.23 | 0.837 |
oleic acid (μmol/L) | 2.2±0.21 | 2.9±0.22 | 1.7±0.08 | 2.82±0.69 | 0.996 |
total free fatty acids (μmol/L) | 12.53±1.95 | 22±2.7 | 15±2.3 | 21.82±0.94 | 0.999 |
HCG was fed a standard chow and three other groups were fed a 60% fructose diet for 8 weeks. In Pio and RDE groups, after the first 6 weeks, animals were treated by pioglitazone (10 mg/kg/day) or rosa damascena extract (100 mg/kg/day) for 2 weeks. FFAs were analyzed by gas chromatography as free fatty acid methyl esters after extraction from TLC plates. All data are presented as Mean± SEM. (n=8)
HCG: healthy control group, Con: control, Pio: pioglitazone, RDE: Rosa damascene extract