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Effects of different concentrations (10–1000 μM) of NMDA on cell viability in SH-SY5Y cell. NMDA (100 μM, 500 μM, and 1000 μM) decreased cell viability at 6 h, 12 h, and 24 h after NMDA exposure for 2 h (P < 0.05). Only at 12 h and 24 h after NMDA (10 μM), treatment was significant (P < 0.05). Numbers represent the percentage of the living cells normalized to the control. Each value represents the mean ± S.E.M. of six independent experiments. ∗P < 0.05 versus the control group.
