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Effect of iodonium analogs on cellular respiration in HT-29 cells. The data represent the mean ± standard deviation (SD) of 3 independent experiments.
| Iodonium analog | 30-min treatment IC50 (nM) | 60-min treatment IC50 (nM) | 24-h treatment IC50 (nM) |
|---|---|---|---|
| DPI | 8,283 ±1,627 | 4,571 ± 745 | 200 ± 245 |
| 104 | 5,964 ±2,816 | 1,472 ± 660 | 74 ± 54 |
| 140 | 678 ±201 | 475 ± 116 | 76 ± 21 |
| 392 | 5,090 ±1,439 | 2,182 ± 410 | 801 ± 194 |
| 428 | 1,538 ±1,450 | 211 ± 33 | 45 ± 23 |
| 521 | 1,667 ±81 | 1,000 ± 14 | No effect |
