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. 2017 Sep 20;8:1801. doi: 10.3389/fmicb.2017.01801

FIGURE 4.

FIGURE 4

Hypothetical model for miRNA-mediated gene silencing in plant-virus interaction. Invading viruses can trigger the production of plant endogenous miRNAs. In addition to specifically repressing the expression of host genes, the miRNAs can target viral mRNA for degradation. To counteract host miRNA-mediated gene silencing, viruses most notably express viral suppressors of RNA silencing (VSRs) to avoid host RNA silencing. VSRs can not only interfere with host miRNA function, but can also repress naturally occurring silencing of host R genes. Although plant virus-derived miRNAs have not yet been discovered, we illustrate hypothetical viral strategies, including miRNA-mediated repression of the host and viral transcripts.