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. 2017 Sep 20;8:670. doi: 10.3389/fphys.2017.00670

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Copyright © 2017 Gaudry and Campbell.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Maximum likelihood gene tree of UCP1, UCP2, and UCP3 coding sequences (N = 448) modified from Gaudry et al. (2017) to include the 16 additional species with recently available genome projects (see Table 1). The stem placental mammal branches are indicated in blue. Note that the UCP1 stem placental branch is much longer than those of UCP2 and UCP3, demonstrating a greater number of nucleotide substitutions per site. Placental mammal genes are highlighted with blue boxes. The tree was rooted with the western clawed frog (Xenopus tropicalis) UCP3.