Table 1.
Presence and absence of the UCP1 enhancer, putative regulatory region (PPR), and CpG island in 139 mammalian species.
| Species name | Enhancer | PPR | CPG island | Accession number |
|---|---|---|---|---|
| MONTREMATA | ||||
| Ornithorhynchus anatinus | X | X | X | NW_001794248.1 |
| MARSUPIALIA | ||||
| Monodelphis domestica | X | X | X | AAFR03015618.1 |
| Macropus eugenii | / | / | X | ABQO020217652.1 |
| Sarcophilus harrisii | / | / | X | AEFK01228715.1 |
| XENARTHRA | ||||
| Choloepus hoffmanni | X | / | / | |
| Dasypus novemcinctus | X | X | Yes | AAGV03181320.1 |
| Mylodon darwinii | Yes | / | / | SRX327588 |
| AFROTHERIA | ||||
| Chrysochloris asiatica | Yes | Yes | X | AMDV01244955.1 |
| Dugong dugon | Yes | Yes | / | MF871621 |
| Echinops telfairi | Yes | Yes | Yes | AAIY02209271.1 |
| Elephantulus edwardii | Yes | Yes | X | AMGZ01097263.1 |
| Elephas maximus | Yes | Yes | Yes | SRX1015608; SRX1015606; SRX1015604; SRX1015603 |
| Hydrodamalis gigas | Yes | / | / | MF871622 |
| Loxodonta africana | Yes | Yes | Yes | AAGU03034821.1 |
| Mammuthus primigenius | Yes | Yes | / | SRX1015727; SRX1015732; SRX1015743; SRX1015748; SRX001906; ERP008929 |
| Orycteropus afer | Yes | Yes | X | ALYB01104541.1 |
| Procavia capensis | X | Yes | Yes | ABRQ02143236.1 |
| Trichechus manatus latirostris | Yes | Yes | Yes | AHIN01109623.1 |
| LAURASIATHERIA | ||||
| Acinonyx jubatus | Yes | Yes | Yes | LLWD01000416.1 |
| Ailuropoda melanoleuca | Yes | Yes | Yes | LNAT01000144.1 |
| Balaena mysticetus | Yes | Yes | Yes | SRX790318, SRX790317, SRX790316, SRX790303, SRX790319 |
| Balaenoptera acutorostrata | Yes | Yes | Yes | ATDI01065547.1 |
| Balaenoptera bonaerensis | Yes | Yes | Yes | BAUQ01197845.1 |
| Balaenoptera physalus | Yes | Yes | Yes | SRX1571086, SRX323050 |
| Bison bison | Yes | Yes | Yes | JPYT01100523.1 |
| Bos grunniens | Yes | Yes | Yes | AGSK01075302.1 |
| Bos indicus | / | Yes | / | AGFL01142554.1 |
| Bos taurus | Yes | Yes | Yes | DAAA02044420.1 |
| Bubalus bubalis | Yes | Yes | Yes | AWWX01630119.1 |
| Camelus dromedarius * | Yes | Yes | Yes | LSZX01012659.1 |
| Camelus ferus | Yes | Yes | Yes | AGVR01051296.1; AGVR01051297.1 |
| Canis lupus familiaris | Yes | X | / | AAEX03011713.1 |
| Capra aegagrus | Yes | Yes | Yes | CBYH010071014.1 |
| Capra hircus | Yes | Yes | / | AJPT01162992.1; AJPT01162993.1 |
| Capreolus capreolus | Yes | Yes | Yes | CCMK010092645.1; CCMK010104759.1 |
| Ceratotherium simum | Yes | Yes | Yes | AKZM01017598.1 |
| Coelodonta antiquitatis | Yes | Yes | Yes | MF871623 |
| Condylura cristata | Yes | X | X | AJFV01047153.1 |
| Dicerorhinus sumatrensis | Yes | Yes | Yes | MF871625 |
| Diceros bicornis | Yes | Yes | Yes | MF871624 |
| Eidolon helvum | Yes | Yes | / | AWHC01286101.1; AWHC01029981.1 |
| Eptesicus fuscus | Yes | X | Yes | ALEH01005956.1 |
| Equus asinus | Yes | Yes | Yes | JREZ01000001.1 |
| Equus caballus | Yes | Yes | / | AAWR02018850.1; AAWR02018851.1 |
| Equus przewalskii | Yes | Yes | Yes | ATBW01036321.1; ATBW01036322.1 |
| Erinaceus europaeus | / | / | X | AMDU01193160.1; AMDU01193161.1; AMDU01193162.1 |
| Felis catus | Yes | Yes | Yes | AANG02062919.1 |
| Giraffa camelopardalis * | Yes | Yes | X | LVKQ01071482.1 |
| Hipposideros armiger * | Yes | Yes | Yes | NW_017731683.1 |
| Leptonychotes weddellii | Yes | Yes | Yes | APMU01115165.1; APMU01141180.1 |
| Lipotes vexillifer | Yes | Yes | Yes | AUPI01000024.1 |
| Lycaon pictus * | Yes | X | / | LPRB01000019.1 |
| Manis javanica * | X | X | X | NW_016530114.1 |
| Manis pentadactyla | X | X | X | JPTV01131901.1 |
| Megaderma lyra | Yes | / | / | AWHB01167753.1; AWHB01348443.1; AWHB01348444.1 |
| Miniopterus natalensis * | Yes | X | Yes | NW_015504404.1 |
| Mustela putorius furo | Yes | Yes | Yes | AGTQ01041845.1 |
| Myotis brandtii | Yes | X | Yes | ANKR01273867.1; ANKR01273868.1 |
| Myotis davidii | Yes | X | Yes | ALWT01125743.1 |
| Myotis lucifugus | Yes | X | Yes | AAPE02001462.1 |
| Odobenus rosmarus | Yes | Yes | Yes | ANOP01028105.1 |
| Okapia johnstoni * | Yes | Yes | Yes | LVCL010093660.1; LVCL010093662.1 |
| Orcinus orca | X | X | X | ANOL02004931.1 |
| Ovis aries | Yes | Yes | Yes | AMGL01037664.1; JN604985.1 |
| Panthera pardus * | Yes | Yes | Yes | NW_017619848.1 |
| Panthera tigris altaica | Yes | Yes | Yes | ATCQ01112915.1 |
| Panthera uncia | Yes | Yes | / | SRX273036 |
| Pantholops hodgsonii | Yes | Yes | Yes | AGTT01188813.1 |
| Physeter macrocephalus | X | Yes | Yes | AWZP01062081.1 |
| Pteropus alecto | Yes | Yes | Yes | ALWS01011689.1 |
| Pteropus vampyrus | Yes | Yes | Yes | ABRP02126915.1 |
| Rhinoceros unicornis | Yes | Yes | Yes | MF871626 |
| Rhinolophus ferrumequinum | Yes | Yes | Yes | AWHA01040305.1 |
| Rhinolophus sinicus * | Yes | Yes | Yes | NW_017738992.1 |
| Rousettus aegyptiacus * | Yes | Yes | Yes | NW_015494583.1 |
| Sorex araneus | Yes | X | Yes | AALT02056093.1 |
| Sus cebrifrons | Yes | / | / | ERX953604-ERX953626; ERX149172 |
| Sus scrofa | Yes | X | X | LUXQ01106311.1 |
| Sus verrucosus | Yes | / | / | ERX1054048-ERX1054067; ERX149174 |
| Tapirus indicus | Yes | / | Yes | MF871627 |
| Tursiops truncatus | X | X | X | ABRN02199412.1 |
| Ursus maritimus | Yes | Yes | / | AVOR01014285.1; AVOR01014286.1 |
| Vicugna pacos | Yes | Yes | Yes | ABRR02134987.1; ABRR02134989.1 |
| EUARCHONTOGLIRES | ||||
| Aotus nancymaae | Yes | Yes | Yes | JYKP01215429.1 |
| Apodemus sylvaticus | Yes | / | X | LIPJ01452544.1; LIPJ01184746.1; LIPJ01447868.1; LIPJ01014497.1 |
| Callithrix jacchus | Yes | Yes | Yes | ACFV01002817.1 |
| Cavia aperea | / | / | / | AVPZ01000778.1 |
| Cavia porcellus | Yes | Yes | Yes | AAKN02011801.1 |
| Cebus capuchinis * | Yes | Yes | Yes | NW_016107319.1 |
| Cercocebus atys | Yes | Yes | Yes | JZLG01060688.1 |
| Chinchilla lanigera | Yes | Yes | Yes | AGCD01027651.1 |
| Chlorocebus sabaeus | Yes | Yes | Yes | AQIB01017419.1 |
| Colobus angolensis | Yes | Yes | Yes | JYKR01122839.1 |
| Cricetulus griseus | Yes | Yes | X | AFTD01128393.1; AFTD01128394.1 |
| Daubentonia madagascariensis | Yes | Yes | / | AGTM011584638.1; AGTM011584996.1; AGTM011708528.1; AGTM012010142.1; AGTM011594144.1 |
| Dipodomys ordii | Yes | X | Yes | ABRO02057411.1 |
| Ellobius lutescens * | Yes | X | Yes | LOEQ01000193.1 |
| Ellobius talpinus * | Yes | X | Yes | LOJH01032235.1 |
| Eulemur flavifrons | Yes | Yes | Yes | LGHW01000184.1 |
| Eulemur macaco | Yes | Yes | Yes | LGHX01000184.1 |
| Fukomys damarensis | Yes | Yes | Yes | AYUG01151056.1 |
| Galeopterus variegatus | Yes | Yes | / | JMZW01045215.1; JMZW01045216.1 |
| Gorilla gorilla gorilla | Yes | Yes | Yes | NW_004002547.1 |
| Heterocephalus glaber | Yes | Yes | Yes | AFSB01162372.1; AFSB01162373.1 |
| Homo sapiens | Yes | Yes | Yes | NG_012139.1 |
| Jaculus jaculus | Yes | Yes | Yes | AKZC01091543.1 |
| Macaca fascicularis | Yes | Yes | Yes | CAEC01514737.1 |
| Macaca mulatta | Yes | Yes | Yes | AANU01271750.1 |
| Macaca nemestrina | Yes | Yes | Yes | JZLF01028562.1 |
| Mandrillus leucophaeus | Yes | Yes | Yes | JYKQ01107154.1; JYKQ01107155.1 |
| Marmota marmota | Yes | Yes | Yes | CZRN01000015.1 |
| Mesocricetus auratus | Yes | X | Yes | APMT01116524.1; NM_001281332.1 |
| Microcebus murinus | Yes | Yes | Yes | ABDC01082367.1 |
| Microtus agrestis | Yes | X | Yes | LIQJ01004042.1 |
| Microtus ochrogaster | Yes | X | X | AHZW01157105.1; AHZW01157106.1 |
| Mus musculus | Yes | X | X | CAAA01024310.1 |
| Mus spretus * | Yes | X | X | LVXV01001867.1 |
| Myodes glareolus | Yes | / | / | LIPI01003929.1 |
| Nannospalax galili | Yes | Yes | X | AXCS01128925.1 |
| Nasalis larvatus | Yes | Yes | Yes | JMHX01319533.1 |
| Neotoma lepida * | / | / | X | LZPO01075894.1 |
| Nomascus leucogenys | Yes | Yes | Yes | ADFV01177960.1 |
| Ochotona princeps | Yes | X | X | ALIT01060999.1 |
| Octodon degus | Yes | Yes | Yes | AJSA01193669.1; AJSA01193670.1; AJSA01193671.1 |
| Oryctolagus cuniculus | Yes | Yes | Yes | AAGW02045633.1 |
| Otolemur garnettii | Yes | Yes | X | AAQR03074138.1 |
| Pan paniscus | Yes | Yes | Yes | AJFE01070904.1 |
| Pan troglodytes | Yes | Yes | / | AACZ03032212.1; AACZ03032213.1 |
| Papio anubis | Yes | Yes | Yes | AHZZ01043343.1 |
| Peromyscus maniculatus | Yes | X | X | AYHN01134223.1 |
| Pongo abelii | Yes | Yes | Yes | ABGA01062109.1 |
| Propithecus coquereli | Yes | Yes | Yes | JZKE01017273.1 |
| Rattus norvegicus | Yes | X | X | AAHX01097782.1 |
| Rhinopithecus bieti * | Yes | Yes | Yes | NW_016805762.1 |
| Rhinopithecus roxellana | Yes | Yes | Yes | JABR01098768.1 |
| Saimiri boliviensis | Yes | Yes | Yes | AGCE01051213.1 |
| Spermophilus tridecemlineatus | Yes | Yes | Yes | AGTP01049378.1 |
| Tarsius syrichta | Yes | Yes | / | ABRT02355486.1 |
| Tupaia belangeri chinensis | Yes | Yes | Yes | ALAR01031045.1 |
Xs = absent, / = inconclusive due to insufficient data,
*
= 16 species with recently published genome projects since the Gaudry et al. (2017) publication. Accession numbers are also provided for contigs and SRA projects.