Figure 2.

The evolution of the reaction coordinate, d, of all 63 models during the ABMD simulation. The eight models that were selected to evaluate the free energies using umbrella sampling simulations are colored (red, magenta, and brown in LEFTs 1–3; blue, cyan, and purple in RIGHTs 1–3; and dark green and light green in PARALLEL 1–2, respectively). To see this figure in color, go online.