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. 2017 Aug 8;7(8):e1197. doi: 10.1038/tp.2017.137

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Copyright © 2017 The Author(s)

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(a) Hyperperfusion in bilateral basal ganglia in mastocytosis patients with white matter abnormalities (WMA): analysis of variance (ANOVA) test for the three groups (WMA patients, non-WMA patients and controls) at the level P=0.001 uncorrected, peak voxel in the left putamen (x=−18, y=12, z=−11), P=0.03 corrected. (b) Cerebral blood flow measured with MRI/ASL (arbitrary units) in the left putamen (x=−18, y=12, z=−11). ***p<0.001. WMA patients had a significant increase in cerebral blood flow in this region compared with non-WMA patients (P<0.001) and to control subjects (P<0.001). Non-WMA patients did not differ from controls. Error bars represent standard error of the mean (s.e.m.). (c) Significant correlation between left putamen perfusion and factors 3, that is, motivation, arising from the factor analysis of SCL90 depression dimension. The shaded area represents the 95% CI. ASL, arterial spin labeling; CI, confidence interval; MRI, magnetic resonance imaging; NS, not significant.