Table 1. Functional enrichment of differentially expressed genes.
Expression | Term | Fold enrichment | P-value | BenjaminiQ-value |
---|---|---|---|---|
Upregulation | GO:0001568~blood vessel development | 4.06 | 6.06E−11 | 1.50E−07 |
GO:0001944~vasculature development | 3.96 | 1.13E−10 | 1.40E−07 | |
GO:0001525~angiogenesis | 4.62 | 1.03E−08 | 8.46E−06 | |
GO:0048514~blood vessel morphogenesis | 3.83 | 1.75E−08 | 1.08E−05 | |
GO:0009615~response to virus | 5.14 | 6.40E−08 | 3.17E−05 | |
GO:0005576~extracellular region | 1.66 | 1.08E−07 | 3.56E−05 | |
GO:0030198~extracellular matrix organization | 5.08 | 1.90E−07 | 7.84E−05 | |
GO:0042127~regulation of cell proliferation | 2.13 | 2.20E−07 | 7.78E−05 | |
GO:0044421~extracellular region part | 2.04 | 2.29E−07 | 3.77E−05 | |
GO:0006955~immune response | 2.21 | 3.36E−07 | 1.04E−04 | |
GO:0009611~response to wounding | 2.29 | 2.95E−06 | 8.10E−04 | |
GO:0022610~biological adhesion | 2.09 | 2.98E−06 | 7.37E−04 | |
GO:0051270~regulation of cell motion | 3.38 | 3.95E−06 | 8.88E−04 | |
GO:0007155~cell adhesion | 2.04 | 6.72E−06 | 1.28E−03 | |
GO:0032393~MHC class I receptor activity | 13.23 | 7.98E−06 | 4.99E−03 | |
GO:0006952~defense response | 2.02 | 3.79E−05 | 5.50E−03 | |
GO:0006954~inflammatory response | 2.49 | 4.98E−05 | 6.83E−03 | |
GO:0019882~antigen processing and presentation | 4.50 | 6.58E−05 | 8.10E−03 | |
Downregulation | GO:0007268~synaptic transmission | 5.94 | 2.33E−08 | 2.59E−05 |
GO:0007610~behavior | 4.44 | 9.56E−08 | 5.30E−05 | |
GO:0019226~transmission of nerve impulse | 5.05 | 2.15E−07 | 7.94E−05 | |
GO:0006928~cell motion | 3.72 | 1.15E−05 | 2.54E−03 | |
GO:0030534~adult behavior | 9.68 | 1.75E−05 | 3.23E−03 | |
GO:0007218~neuropeptide signaling pathway | 8.95 | 2.92E−05 | 4.62E−03 | |
GO:0005509~calcium ion binding | 2.62 | 4.63E−05 | 7.89E−03 | |
GO:0051969~regulation of transmission of nerve impulse | 6.37 | 8.08E−05 | 9.91E−03 | |
GO:0007409~axonogenesis | 5.39 | 9.55E−05 | 1.05E−02 | |
GO:0031644~regulation of neurological system process | 6.12 | 1.07E−04 | 1.07E−02 | |
GO:0050877~neurological system process | 2.24 | 1.68E−04 | 1.54E−02 | |
GO:0048667~cell morphogenesis involved in neuron differentiation | 4.98 | 1.75E−04 | 1.48E−02 | |
GO:0048812~neuron projection morphogenesis | 4.89 | 2.01E−04 | 1.58E−02 | |
GO:0046873~metal ion transmembrane transporter activity | 3.83 | 2.81E−04 | 3.15E−02 | |
GO:0005261~cation channel activity | 4.19 | 2.82E−04 | 2.39E−02 | |
GO:0005216~ion channel activity | 3.53 | 2.96E−04 | 2.01E−02 | |
GO:0050804~regulation of synaptic transmission | 6.12 | 3.21E−04 | 2.34E−02 | |
GO:0007186~G-protein-coupled receptor protein signaling pathway | 2.22 | 3.61E−04 | 2.47E−02 |
Abbreviations: GO, gene ontology; MHC, major histocompatibility complex.