Table 1. Amygdala and BLA receptors mediating neurotransmission.
| Type | Location | Function | Comment | Refs |
|---|---|---|---|---|
| GABA | ||||
| GABAA | PN | Inhibit PN | 5 | |
| GABAB | Presynaptic GABA | Inhibit GABA release | ↑PN excitability | 39 |
| GABAB | Postsynaptic GABA | Inhibit GABA release | 55 | |
| Cannabinoid | ||||
| CB1 | Presynaptic GABA | Inhibit GABA release | 37 | |
| Serotonin | ||||
| 5HT1A | Presynaptic GABA | Inhibit GABA release | 38 | |
| 5HT1A | PN | ↓ PN excitability | 38 | |
| 5HT2 | Postsynaptic GABA | ↑ GABA release | Inhibit PN | 54 |
| 5HT2A | PN | ↑ PN excitability | 58 | |
| Dopamine | ||||
| D1R | PN | ↑ PN excitability | 44, 45 | |
| D2R | Presynaptic GAB | Inhibit GABA release | 42, 43 | |
| Adrenergic | ||||
| α1A | Presynaptic GABA | ↑ GABA release | 22 | |
| α2 | Presynaptic GABA | ↑ GABA release | 46 | |
| β | Excite PN | Via SK channel and AHP | ||
| Cholinergic | ||||
| nAChRs-α7 | Presynaptic GABA | ↑ GABA release | 48, 49 | |
| M1 | PN | ↑ PN excitability | 57 | |
| Glutamate | ||||
| AMPAR | Postsynaptic GABA | ↑ GABA release | LTP: GABA neuron | 51, 52 |
| AMPAR | PN | Excite PN | 56 | |
| NMDAR | Postsynaptic GABA | ↑ GABA release | LTP: GABA neuron | 51 |
| NMDAR | PNs | Excite PN | 56 | |
| Adenosine | ||||
| A1 | Presynaptic Glut | Inhibit glutamate release | 65 | |
| A2A | PN | ↑ PN excitability | Inhibit AHP | 62 |
Abbreviations: AHP, afterhyperpolarization; AMPAR, α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor; BLS, basolateral amygdala; LTP, long-term potentiation; nAChR, nicotinic cholinergic receptor; NMDAR, N-methyl-d-aspartate receptor; PN, principal neuron.