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. 2017 Aug 15;7(8):e1204. doi: 10.1038/tp.2017.180

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Copyright © 2017 The Author(s)

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/

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Group differences during worry induction and reappraisal (unadjusted for core depressive symptoms). Independent t-tests comparing the mean cerebral blood flow (CBF) in the healthy compared to the generalized anxiety disorder (GAD) group during worry induction (minus rest, top) and reappraisal (bottom). Areas where CBF was greater in the GAD group are shown in red/warm colors and healthy greater than GAD in blue/cool colors. The colors indicate T-statistics from the independent t-test. Yellow arrows indicate regions that survived multiple comparisons correction via a non-parametric method (SnPM). These results did not pass significance threshold after adjusting for core depressive symptoms (HDRS).