Skip to main content
. 2017 Aug 29;7(8):e1220. doi: 10.1038/tp.2017.190

Table 2. Comparison of erythrocyte membrane phosphatidylethanolamine lipid levels at baseline in patients with mood disorder, psychosis, anxity disorder or other psychiatric disorders after 7 years.

  Mood vs no mood (n=26 vs n=43)
Psychosis vs no psychosis (n=20 vs n=49)
Anxiety vs no anxiety (n=19 vs n=50)
Other vs no other (n=11 vs n=58)
  Effect size (Cohen’sd) P-value Effect size (Cohen’sd) P-value Effect size (Cohen’sd) P-value Effect size (Cohen’sd) P-value
LC ω -6 Fatty Acids
 Linolenic acid (18:2n-6)a −0.553 0.035 0.139 0.543 0.003 0.990 −0.178 0.610
 γ-Linolenic acid (18:3n-6) 0.582 0.023 −0.172 0.509 0.260 0.346 0.161 0.603
 Dihomo-γ-linolenic acid (20:3n-6) 0.299 0.229 −0.114 0.683 −0.127 0.645 0.264 0.458
 Arachidonic acid (20:4n-6) −0.191 0.447 −0.316 0.213 −0.211 0.410 −0.275 0.371
 Docosadienoic acid (22:2n-6) 0.612 0.017 −0.213 0.420 0.015 0.954 −0.188 0.579
 Adrenic acid (22:4n-6) 0.243 0.327 −0.242 0.344 −0.148 0.592 −0.014 0.965
                 
LC ω -3 Fatty Acids
 a-Linolenic acid (18:3n-3)a −0.073 0.775 0.106 0.696 −0.307 0.272 0.157 0.650
 Eicosapentaenoic acid (20:5n-3)a −0.729 0.003 −0.134 0.612 −0.467 0.077 −0.233 0.497
 Docosapentaenoic acid (22:5n-3) −0.443 0.076 0.018 0.942 −0.134 0.616 −0.058 0.877
 Docosahexaenoic acid (22:6n-3) −0.618 0.010 −0.092 0.749 −0.486 0.090 −0.625 0.087
                 
Sums and Ratios
 Sum of LC ω-6 fatty acidsb −0.199 0.413 −0.237 0.349 −0.149 0.565 −0.235 0.541
 Sum of LC ω-3 fatty acidsb −0.699 0.004 −0.069 0.911 −0.436 0.111 −0.472 0.197
 LC ω -6 to LC ω-3 fatty acids ratio 0.610 0.012 0.008 0.975 0.278 0.335 0.283 0.435
a

Log transformed.

b

Sum comprises long-chain fatty acids ⩾20 carbon atoms.