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. Author manuscript; available in PMC: 2018 Apr 14.
Published in final edited form as: Science. 2017 Apr 14;356(6334):eaaf7230. doi: 10.1126/science.aaf7230

Fig. 6.

Fig. 6

Cross-couplings of primary alkyl electrophiles: Early (pre-2000) methods. A: Examples. B: An application in the total synthesis of a natural product. C: Use of nucleophiles that have improved functional-group compatibility.