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. Author manuscript; available in PMC: 2017 Sep 25.
Published in final edited form as: Exp Lung Res. 2010 Dec 4;37(3):155–161. doi: 10.3109/01902148.2010.516057

TABLE 1.

GSH Contents in Lung Tissue Homogenates

Diet RA
O2
WT spc–mthGR WT spc–mthGR
Control 0.87 ± 0.06 0.95 ± 0.04 0.94 ± 0.12 0.66 ± 0.10
Riboflavin 1.28 ± 0.12# 0.75 ± 0.15*,# 1.43 ± 0.30*,# 0.76 ± 0.10*

Note. Transgenic spc–mthGR mice and WT littermates were fed either a control or high-riboflavin diet beginning at 3 weeks of age, and at 6 weeks of age were exposed to RA or >95% O2 for 84 hours. GSH concentrations were measured in 10% lung homogenates as described in Methods. Data were non-normal, and were transformed to square root and analyzed by 3-way ANOVA. An individual effect of transgene and an interaction between transgene and diet were detected. Two-way ANOVA with modified t test post hoc was performed with exposure as a fixed factor. An individual effect of transgene was detected.

*

Difference compared to WT, same diet.

#

difference between diets, same genotype; n = 5–22; P ≤ .05.