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Primary and secondary bile acids accumulate in the serum of the Oat3KO. A, metabolites associated with primary bile acid metabolism; B, metabolites associated with the metabolism of secondary bile acids. As above, metabolites are colored and sized based upon their magnitude of change (size) and direction of change (color; dark red (p ≤ 0.05); bright red (0.05 < p < 0.10); pale red (p < 0.10)).
