Figure 2.
p63α up-regulation promoted invasion in human high invasive BC cells. A–C, Western blotting was used to evaluate the stable ectopic expression of p63α in p63α transfectants as indicated. D–G, the invasion abilities of p63α stable transfectants and their scramble vector transfectants were evaluated by using BD BioCoatTM MatrigelTM Invasion Chamber. The asterisk (*) indicates a significant difference in invasion ability between p63α-overexpressed cells and their scramble vector transfectants (p < 0.05). The bars are presented as the mean ± S.D. from three independent experiments. H–J, cell proliferation was determined in the indicated transfectants using ATP assay. The asterisk (*) indicates a significant inhibition as compared with the scramble vector transfectants.