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. 2017 Sep 15;130(18):3173–3185. doi: 10.1242/jcs.194571

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© 2017. Published by The Company of Biologists Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Fig. 1. — Examples of S. pombe cells from plug assays that exhibit the different classes of cell shape defects. Examples of (A) misshapen, (B) vacuolated, (C) swollen cell tip, (D) lysis, (E) control SAK950, (F) small, (G) rounded, (H) multiseptated, (I) elongated, (J) asymmetric septum cell shape defects. Black arrows in J indicate asymmetrically placed septa or an asymmetrically dividing cell. All cells within the halo, produced by the secreted bioactivity, were visually screened, and representative images from one screen are shown. Scale bars: 10 µm.