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. 2017 Sep 15;130(18):2971–2983. doi: 10.1242/jcs.205948

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© 2017. Published by The Company of Biologists Ltd

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Fig. 4. — FN substrate is necessary for Tiam1- but not ITSN1-induced optotaxis. (A) Rose plots, FMI graphs and velocity plots representing migration vectors for Tiam1-Micro- and iLID-CAAX-expressing fibroblasts plated on FN or poly-L-lysine (poly-LL). (B) Rose plots, FMI graphs and velocity plots representing migration vectors for Tiam1-Micro- and iLID-CAAX-expressing fibroblasts plated on fibronectin or poly-L-lysine. Blue triangles represent the light gradient. Error bars are the 95% c.i. *P<0.005. Refer to Table S1 for experimental details.