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The hypertrophied CS muscle had increased phosphorylated (P) AMPKα compared to normal. A) Note the variability in western blot expression of P-AMPKα in GRMD dog samples. B) P-AMPKα was normalized to Total AMPKα protein and increased compared to normal samples. * = p < 0.05. C) P-AMPKα was positively correlated with CS circumference.
