Table 1. Cytokines and chemokines increased in DBA/2 relative to C57BL/6 mice in response to influenza virus infection. The virus strain used in each study is indicated.

			Days Post Infection
	1	2	3	4	5	6	7
			CYTOKINES
G-CSF (CSF3)	-	-	-	-	X31	X31	X31
	-	PR8	PR8	PR8	-	-	-
	-	-	HK213	-	-	-	-
IFNα	-	HK213#	HK213	-	-	-	-
	swH1N1*	swH1N1*	-	-	-	-	-
IFNβ	-	-	HK213	-	-	-	-
	swH1N1*	-	-	-	-	-	-
IFNγ	-	-	-	-	X31	X31	X31
	-	-	-	-	-	swH1N1	swH1N1
IL-1α	-	PR8	PR8	-	-	-	-
IL-1β	-	-	-	-	X31*	X31*	X31*
	-	-	swH1N1	swH1N1	swH1N1	-	-
IL-5	-	PR8	PR8	PR8	-	-	-
IL-6	X31	-	X31	-	X31	X31	X31
	-	-	swH1N1	swH1N1	swH1N1	swH1N1	swH1N1
	-	PR8	PR8	PR8	-	-	-
IL-12	-	-	-	PR8	-	-	-
TNFα	-	-	X31	-	X31	X31	X31
	-	HK213#	HK213	-	-	-	-
	-	-	-	swH1N1	swH1N1	swH1N1	swH1N1
			CHEMOKINES
IP-10	X31	-	X31	-	X31	X31	X31
	-	PR8	PR8	PR8	-	-	-
KC	X31	-	X31	-	X31	X31	X31
	-	PR8	PR8	PR8	-	-	-
	-	-	swH1N1	swH1N1	swH1N1	swH1N1	swH1N1
MCP-1 (CCL2)	X31	-	X31	-	X31	X31	X31
	-	PR8	PR8	PR8	-	-	-
	-	HK213#	-	-	-	-	-
	-	-	-	swH1N1	swH1N1	swH1N1	swH1N1
MIG	-	PR8	PR8	PR8	-	-	-
MIP1α	X31	-	X31	-	X31	X31	X31
	-	PR8	PR8	PR8	-	-	-
	-	-	-	-	-	swH1N1	swH1N1
MIP2 (CXCL2)	-	-	HK213	-	-	-	-
	-	PR8	PR8	PR8	-	-	-
	swH1N1	-	swH1N1	swH1N1	swH1N1	swH1N1	-
RANTES	-	PR8	PR8	PR8	-	-	-

X31 – A/Aichi/2/68 (H3N2) x31 (6:2 reassortment with PR8) [7,59]

PR8 – mouse-adapted A/Puerto Rico/8/34 (H1N1) [5]


HK213^# – reverse genetics A/Hong Kong/213/2003 (PB1 segment A/Chicken/Hong Kong/Y0562/2002) (H5N1) [28]

HK213 – reverse genetics A/Hong Kong/213/2003 (PB1 segment A/Chicken/Hong Kong/Y0562/2002) (H5N1) [6,22]

swH1N1 – mouse-adapted A/Swine/Iowa/4/1976 (H1N1) [23]

-No data available or data available lacks statistical significance


*C57BL/6 > DBA/2