Table 3.

Range of motion.

	UP1306	Glucosamine and chondroitin combination	Placebo	p value
				All three products	UP1306 versus G&C	UP1306 versus placebo
Extension change from baseline to day 84	1.65 ± 2.43 (43)	1.93 ± 3.16 (44)	1.54 ± 1.89 (41)	0.763	0.445	0.683
	0 (−1–10)	0 (−2–14)	2 (−2–6)
	p < 0.001∗	p < 0.001∗	p < 0.001∗
Flexion change from baseline to day 84	−8.3 ± 7.1 (43)	−8.0 ± 8.2 (44)	−7.8 ± 8.2 (41)	0.944	0.867	0.930
	−8 (−25–8)	−6 (−25–4)	−6 (−32–7)
	p < 0.001∗	p < 0.001∗	p < 0.001∗

^∗Significant: p ≤ 0.05.