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. Author manuscript; available in PMC: 2017 Sep 25.
Published in final edited form as: J Am Soc Mass Spectrom. 2017 Jan 3;28(5):818–826. doi: 10.1007/s13361-016-1565-z

Figure 1.

Figure 1

The deamidation of asparagine mechanism. Asparagine forms a five-membered succinimide ring intermediate from an intramolecular attack, and then hydrolyzes to form either aspartyl and isoaspartyl peptides (created using ChemDoodle by iChemLabs)