Table 4.

Subject Experience Questionnaire by Metabolism Genotype

	Total Adverse Experience Score, Mean (95% CI)				CNS Adverse Experience Score, Mean (95% CI)
	Extensive	Inter-mediate	Slow	p value*	Extensive	Inter-mediate	Slow	P value*
Month 1	5.2 (4.1, 6.2)	4.6 (3.9, 5.4)	2.8 (1.7, 3.9)	<0.01	3.0 (2.3, 3.7)	2.8 (2.3, 3.3)	1.6 (0.9, 2.4)	<0.02
Month 6	2.3 (1.7, 3.0)	2.1, (1.6, 2.5)	1.6 (0.9, 2.3)	0.34	1.3 (0.9, 1.7)	1.2 (0.9, 1.5)	0.9 0.5, 1.4)	0.55

^*for differences between groups