Table 2.
Antibiotic selection and prescribed duration of therapy
| Pre-intervention period n=300 |
Intervention period n=200 |
p-value | |
|---|---|---|---|
| Broad gram-negative antibiotic | 152 (51) | 80 (40) | 0.02 |
| Fluoroquinolone | 115 (38) | 50 (25) | .002 |
| Amoxicillin/clavulanate | 37 (12) | 30 (15) | 0.39 |
| Azithromycin | 37 (12) | 39 (20) | 0.03 |
| Metronidazole | 29 (10) | 11 (6) | 0.09 |
| Clindamycin | 26 (9) | 23 (12) | 0.30 |
| Trimethoprim/sulfamethoxazole | 20 (7) | 11 (6) | 0.60 |
| Doxycycline | 19 (6) | 16 (8) | 0.47 |
| Penicillin or amoxicillin | 15 (5) | 6 (3) | 0.27 |
| Clarithromycin | 11 (4) | 2 (1) | 0.07 |
| Nitrofurantoin | 8 (3) | 5 (3) | 0.91 |
| 2nd- and 3rd-generation cephalosporins a | 4 (1) | 4 (2) | 0.72 |
| Other | 10 (3) | 2 (1) | 0.14 |
| Received ≥2 antibiotics | 50 (17) | 21 (11) | 0.05 |
| Total prescribed duration of therapy, median (IQR) | 10 (7–13) | 9 (6–13) | 0.13 |
| Duration of inpatient therapy, median (IQR) | 3 (3–5) | 4 (3–5) | 0.01 |
| Duration of prescribed at discharge, median (IQR) | 6 (4–10) | 5 (3–7) | 0.003 |
a
includes cefdinir, cefixime, cefpodoxime, and cefuroxime