Table.

Clinical Characteristics

Characteristic	Outcome
No. of affected individuals	6
No. of affected individuals clinically examined	5
Age, mean (SD) [range], y
Onset	36 (12) [19–48]
Death	70 (4) [67–75]
Spasticity	Moderate/severe phenotype
Weakness	Mild phenotype, proximal
Muscle wasting	Mild phenotype
Hyperreflexia	Moderate phenotype
Plantar reflex	Extensor
Vibration sensation at ankles	Decreased
Urinary dysfunction	Mild phenotype
Additional features (No. of individuals/total individuals)	Foot deformity (2/5)
Brain MRI	Normal
Neurophysiology	CMT delayed, normal NCS and EMG

Abbreviations: CMT, central motor conduction time; EMG, electromyography; MRI, magnetic resonance imaging; NCS, nerve conduction studies.