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. Author manuscript; available in PMC: 2017 Sep 25.
Published in final edited form as: Breast Cancer Res Treat. 2016 May 5;157(2):395–400. doi: 10.1007/s10549-016-3799-7

Figure 1A.

Figure 1A

Scalp changes in a 49-year-old woman with stage IIA invasive ductal carcinoma, following improper cold cap application procedures for the prevention of CIA (adjuvant TCHP). Post-inflammatory hyperpigmentation over the upper mid-forehead (distal to the frontal hairline), 1 week after the 3rd chemotherapy cycle/cold cap use. Note the arcuate violaceous patch with sharply demarcated borders and localized alopecia. (Inset) Large patch of alopecia on the frontal scalp, approximately 4 weeks after the 3rd chemotherapy cycle/cold cap use.