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Localized alopecia (white dotted lines) on the background of diffuse hair thinning in a 58-year-old woman with ER+/PR+/Her2−, metastatic breast cancer—approximately 3 weeks after the first cold thermal injury (blistering and crusting). The localized alopecia occurred after one instance of cold cap use on a scalp that had already developed diffuse paclitaxel-induced alopecia.
