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. Author manuscript; available in PMC: 2017 Sep 25.
Published in final edited form as: J Nucl Med. 2015 Aug 27;56(12):1942–1947. doi: 10.2967/jnumed.115.160002

FIGURE 5.

FIGURE 5

Vessel-derived mAng1 and mAng2 along with tumor cell SEAP protein secretion are modulated by tumor growth and trebananib therapy. (A) Serum concentration of mAng1 is significantly elevated by day 19 in vehicle-treated group but was maintained at baseline in trebananib-treated group. (B) mAng2 is elevated in both groups. (C) Detection of SEAP is significantly lower in trebananib-treated mice by day 19 after treatment, and plasma SEAP is correlated with THb. SEAP in plasma quoted as ng protein detected in 5 μL of isolated plasma. *P < 0.05.