Table 2. Summary of reported primary outcomes.

Outcomes are reported as combined treatment versus stereotactic radiosurgery alone. Abbreviations: mo = months; OS = overall survival; LC = local control; DBC = distant brain control; HR = hazard ratio; CI = confidence interval; NR = not reported; NS = not significant [29-32].

	Patel, et al. [29]	Silk, et al. [30]	Mathew, et al. [31]	Knisely, et al. [32]
Median  OS (mo)	8.0 vs. 9.1, HR 1.07, p = 0.84	19.9 vs. 4.0, HR 0.31, p < 0.01	NR	21.3 vs. 4.9; HR 0.48, 95% CI, 0.24 - 0.93, p = 0.03
6-mo OS  (%)	79 vs. 69	100 vs. 38	56 vs. 46, p = 0.18	74 vs. 48
12-mo OS  (%)	37 vs. 39	83 vs. 32	33 vs. 24, p = 0.18	70 vs. 34
6-mo LC  (%)	NR	NR	65 vs. 63, p = 0.55	NR
12-mo LC (%)	71 vs. 92, p = 0.40	NR	42 vs. 45, p = 0.55	NR
6-mo DBC (%)	NR	NR	35 vs. 47, p = 0.48	NR
12-mo DBC (%)	13 vs. 29, p = 0.59	NR	16 vs. 29, p = 0.48	NR